Proton therapy is effective in treating many types of cancerous and non-cancerous tumors.

Protons can be controlled with greater precision than X-rays; this means that more energy goes into destroying your tumor and less radiation is delivered to surrounding healthy tissue.1 For this reason, proton therapy is particularly good for treating tumors near healthy organs, including melanoma of the eye. Treating a melanoma of the eye with proton therapy can reduce your radiation exposure to the brain, when compared to X-rays.

Reference

  1. Fowler JF. What can we expect from dose escalation using proton beams? Clin Oncol. 2003;15(1):S10-S15.


PROTON THERAPY RESEARCH


Proton Therapy is an innovative means of cancer treatment that delivers radiation at exact depths to precisely target tumors. Much of the radiation is deposited exactly at the tumor site and then stops, reducing excess radiation to healthy tissue compared to X-rays. X-rays release their maximum dose of radiation quickly after penetrating the skin, potentially damaging healthy tissue and organs on their way to the tumor and as they pass through your body beyond the tumor.

Click on the sources to the right to find out more about proton therapy and the research conducted.

Eye


Hrbacek J, Mishra KK, Kacperek A, Dendale R, Nauraye C, Auger M, Herault J, Daftari IK, Trofimov AV, Shih HA, Chen YL, Denker A, Heufelder J, Horwacik T, Swakon J, Hoehr C, Duzenli C, Pica A, Goudjil F, Mazal A, Thariat J, Weber DC. Practice Patterns Analysis of Ocular Proton Therapy Centers: The International OPTIC Survey. >Int J Radiat Oncol Biol Phys. 2016 May 1;95(1):336-43.

Abstract: http://www.ncbi.nlm.nih.gov/pubmed/27084651

Gragoudas ES, Li W, Goitein M, Lane AM, Munzenrider JE, Egan KM. Evidence-based estimates of outcome in patients irradiated for intraocular melanoma. Arch Ophthalmol. 2002;120(12):1665-1671.

Abstract: http://www.ncbi.nlm.nih.gov/pubmed/12470140

Yock T, Schneider R, Friedman A, Adams J, Fullerton B, Tarbell N. Proton radiotherapy for orbital rhabdomyosarcoma: clinical outcome and a dosimetric comparison with photons. Int J Radiat Oncol Biol Phys. 2005;63(4):1161-1168.

Abstract: http://www.ncbi.nlm.nih.gov/pubmed/15950401

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